The EU aims to become climate-neutral and an economy with net-zero greenhouse gas emissions by 2050. This will affect all activity sectors, from the power/energy sector to industry, agriculture, forestry, among others. While global demand for energy continues to rise, increasing pressure from governments, investors, and consumers to support the decarbonization of the industry has spearheaded radical change. We are witnessing that the energy transition is firmly underway. In recent years we have seen the overhaul of entire business models from a focus on fossil fuels to clean energy, organizational restructures to meet new net zero targets, the sell down of billions worth of fossil fuel assets and a shift in bank appetite towards cleaner fuels and technologies. In Europe, renewable energies overtook fossil fuels in the EU’s energy mix for the first time in 2020. Even though other global economies are on similar transition paths, lots still need to be done to reach the ambitious goals from industries and companies, but also public entities. Despite strengthened legislative measures for environmental protection and reduction in the number of polluted sites, a substantial number of “hot spots” still exist globally. An integration of multiple novel ideas to create linkages between public authorities, industrial partners and the scientific community will be necessary.